Access to the multimedia content of the products.


From 0.5 to 2.5 m² of shelf area
Condenser capacity up to 40 kg
Output for 2R up to 10,000 vials

GMP production equipment for small batches

Compact construction complying with GMP

CIP / SIP equipment

Wide range of optional equipment

Panels for clean rooms


  • GMP Freeze Dryers for Small Batches
  • GMP Freeze Dryers for Small Batches
  • GMP Freeze Dryers for Small Batches
  • GMP Freeze Dryers for Small Batches
  • GMP Freeze Dryers for Small Batches
  • GMP Freeze Dryers for Small Batches

Designed for aseptic batches. Compact and adaptable.

During pharmaceutical and biotechnological development, high value-added and personalized configuration products require a highly demanding process in small batches and in full compliance with regulations and procedures.

The LyoNano model is the best choice for customers developing processes for high value products. It is equipped with technology available in our commercial units but for smaller batch sizes and is in full compliance with commercial regulation and procedure.

Model LyoNano
Shelf area 0.5 m² 1 m² 1.5 m² 2 m²
Shelf dimensions (W x D) 380 x 450 mm
Nº of shelves 3 + 1 6 + 1 9 + 1 12 + 1
Shelves clearance 90 mm 75 mm 90 mm 65 mm
Chamber material Stainless steel AISI 316L
Condenser capacity 30 kg 30 kg 40 kg 40 kg
Condenser temperature -85 ºC
Shelves temperature range from - 60 ºC to +85 ºC
Overall dimensions (W x D x H) 1,600 x 1,300 x 1,800 mm 2,500 x 1,300 x 1,800 mm
Weight 1,500 kg 2,000 kg 2,500 kg 3,000 kg

Optional equipment

The chamber

  • Rectangular chamber

  • Pressureless vessel

  • Injected foam insulation

  • Cooling by cold water circuit

Connection with condenser

  • Butterfly valve

  • Mushroom valve

  • Bottom shelf closing

Ice condenser

  • Integrated underneath, on the same floor

  • Integrated on the side, on the same floor

  • Outside, behind the camera, on the same floor

  • Outside, under the camera, on another floor

Shelves movement

  • Closing system hydraulic piston

  • Bellows

  • Connection with the automatic charging system


  • Chamber and condenser cleaning system

  • Recirculation system with heating

  • Multiple cleaning cycles


  • PED-EN13445

  • ASME

  • Chamber cool-down after SIP

Plant distribution

  • 1st floor

  • 2 floors

  • Passthrough system

Additional elements

  • ATEX (processed with solvents and alcohol)

  • Cold tray loading

  • Frozen tray loading

  • Nucleation technology


  • Piston compressor

  • Screw compressor

  • Liquid nitrogen system

  • Cascade system

  • Cooling system without PCA

  • Compressed air system


  • Full size door

  • Automatic locking

  • Slot front door (constant loading level)

  • Full size sub-door

  • Cooling by cold water circuit

Process sensors

  • Pirani

  • Capacitive

  • Temperature probes (Pt-100 / Thermocouple)

  • Redundant temperature probes (Pt-100 / Thermocouple)

  • Wireless temperature monitoring

  • Full batch traceability software

Control systems

  • Rockwell / Siemens Automation PLC

  • Integrated HMI


  • Electronic recorder

  • Electronic Server and Think Client

  • Cycle optimization technology

Filter vent system

  • Sterilizable

  • Ports for integrity testing

  • Secondary venting cycle

  • Secondary vent filter

  • Water filter integrity test

Vacuum system

  • Sealed vacuum pumps with blowing system

  • Redundancy (additional pump)

  • Dry pumps with blowing system

Always at your disposal!

We look forward to assisting you with your projects and answering your questions and suggestions. Fill in this form and we will contact you as soon as possible.

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