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Freeze-drying equipment manufacturing

Coolvacuum was created to meet the need of the pharmaceutical industry for a reliable and efficient partner who would improve freeze-drying processes in the industry.

After years of in-house development of freeze-drying equipment, the objective of the company shifted towards the integration of complete lines in aseptic filling processes, to guarantee our customers safe and cross-contamination free processes. Thanks to the proximity and good business relationship with the Dara Pharma Group, Coolvacuum is later integrated into the Group through acquisition.

Coolvacuum & Dara Pharma

Owners of the company Coolvacuum (from left to right: Roberto Calvo, Oscar Ral, Manuel Garrote and David Ral).

Manuel Garrote starts his activity as a specialist in the maintenance, adjustment and updating of freeze-drying equipment.

2004 - 2007

Installation and adjustment of the largest freeze dryers in Spain in the pharmaceutical sector.

2008 - 2013

Coolvacuum starts with the design of the first freeze-drying equipment.

2014 - 2015

First Coolvacuum production plant in Terrassa, and refurbishment and construction of the first industrial freeze dryer.

Manufacture of 6 freeze dryers of 30 and 20 m² with centralized cooling system for the Nutritional sector.

The first project for manufacture of a 30 m² pharma freeze dryer for probiotics.


Laboratory and Pilot range launch.


Coolvacuum goes international.
The first GMP production equipment installed in Russia.


The first freeze dryer of 100 m².


The first equipment with the loading system ROW BY ROW.


Dara Pharma acquires Coolvacuum, a freeze dryer manufacturer. This strategic acquisition transforms Dara into a global provider of complete solutions for the pharmaceutical industry. From left to right: Roberto Calvo, David Ral, Manuel Garrote, Oscar Ral, Andreu Antonell and Joan Melé. Launch of the new product family (LyoCompact / LyoCool / LyoPro), offering and integrating the latest technologies at the highest quality.


First integration of freeze-drying equipment into Dara Pharma Group's filling lines and development of the first in-house loading system in a freeze-dryer.