Access to the multimedia content of the products.

Lyotech Center

Coolvacuum LyoTech Center

...is part of the Dara Tech Center.

Located at the Dara Pharma headquarters in Barcelona. Since it was founded in 1996, Dara Pharma has followed a path towards quality, innovation, and technological excellence, a path that could not have been followed without the investment in the search and use of the latest technologies, together with the development of our own prototypes and systems, allowing us to offer the range of solutions to the industry for which Dara is well known today.

Coolvacuum offers complete services, such as:

  • Training courses
  • Recipe development
  • Qualification of recipes
  • Validation of recipes
  • Product characterization
    • Thermal behavior
      • Eutectic temperature
      • Fusion temperature
      • Vitreous transition temperature
      • Collapse temperature
    • Freezing processes (Nucleation)
    • Primary / secondary drying phases
      • Humidity measure by high frequency
      • Humidity measure by Karl Fisher test
  • Cycle adjustment to avoid vial breakage
  • Product quality improvement
    • Turbidity
    • Collapse
    • Pill shrinkage
    • Strata
    • Sedimentation
    • Concentration
    • Colored areas
    • Hardened top coat
    • Meltback
    • Boiling
    • Puffing
  • Freeze-drying cycle time reduction