VLS + LyoPharm by Dara Pharma: Auto Load/Unload for Freeze Dryers

Model	NLS Nest loading system	VLS Vial loading system	VLS⁺ Vial loading system
Load sequence	PUSH-IN	Row by Row PUSH-IN	PULL-IN
Unload sequence	PULL-OUT	Multiple Row PUSH-OUT	PUSH-OUT
Based technology	Robot	Servo cylinder	Servo chain
Output max.	115 "Nest" / h	12,000 uph	24,000 uph

Model

NLS
Nest loading system

VLS
Vial loading system

VLS⁺
Vial loading system

Load sequence

PUSH-IN

Row by Row PUSH-IN

PULL-IN

Unload sequence

PULL-OUT

Multiple Row PUSH-OUT

PUSH-OUT

Based technology

Robot

Servo cylinder

Servo chain

Output max.

115 "Nest" / h

12,000 uph

24,000 uph

Model	LyoPharm
Shelf area	800 x 900 mm	1,200 x 1,200 mm	1,500 x 1,600 mm	1,500 x 2,000 mm
Shelf area (m²)	2.16	2.88	3.6	4.32	5.04	5.76	7.2	8.64	10.08	11.52	12.96	14.4	16.8	19.2	21.6	24	26.4	28.8	30	33	36	39	42	45
Nº of shelves	3	4	5	6	7	8	5	6	7	8	9	10	7	8	9	10	11	12	10	11	12	13	14	15
Shelves clearance (mm)	105	90	75	105	90	75	105	90	75	105	90	75	105	90	75	105	90	75	105	90	75	105	90	75
Chamber width	2,000 mm	2,300 mm	2,500 mm	2,500 mm
Chamber height	2,200 mm	2,500 mm	2,500 mm	2,900 mm	2,500	2,900 mm	3,400 mm	3,400 mm	3,600 mm
Condenser capacity (kg)	40	45	50	65	80	80	120	150	200	200	250	250	300	350	400	450	450	500	600	800
Trays	300 x 400 mm	300 x 400 mm	300 x 400 mm	300 x 400 mm
Condenser temperature	-85 ºC	-85 ºC	-85 ºC	-85 ºC
Shelves temperature range	from -60ºC to +85ºC	from -60ºC to +85ºC	from -60ºC to +85ºC	from -60ºC to +85ºC

Model

LyoPharm

Shelf area

800 x 900 mm

1,200 x 1,200 mm

1,500 x 1,600 mm

1,500 x 2,000 mm

Shelf area (m²)

2.16

2.88

3.6

4.32

5.04

5.76

7.2

8.64

10.08

11.52

12.96

14.4

16.8

19.2

21.6

26.4

28.8

Nº of shelves

Shelves clearance (mm)

105

Chamber width

2,000 mm

2,300 mm

2,500 mm

Chamber height

2,200 mm

2,500 mm

2,900 mm

2,500

2,900 mm

3,400 mm

3,600 mm

Condenser capacity (kg)

120

150

200

250

300

350

400

450

500

600

800

Trays

300 x 400 mm

Condenser temperature

-85 ºC

Shelves temperature range

from -60ºC to +85ºC

Optional equipment

The chamber

Rectangular chamber
Pressureless vessel
Injected foam insulation
Cooling by cold water circuit

Connection with condenser

Butterfly valve
Mushroom valve
Bottom shelf closing

Ice condenser

Integrated underneath, on the same floor
Integrated on the side, on the same floor
Outside, behind the camera, on the same floor
Outside, under the camera, on another floor

Shelves movement

Closing system hydraulic piston
Bellows
Connection with the automatic charging system

CIP

Chamber and condenser cleaning system
Recirculation system with heating
Multiple cleaning cycles

SIP

PED-EN13445
ASME
Chamber cool-down after SIP

Plant distribution

1st floor
2 floors
Passthrough system

Additional elements

ATEX (processed with solvents and alcohol)
Cold tray loading
Frozen tray loading
Nucleation technology

Refrigeration

Piston compressor
Screw compressor
Liquid nitrogen system
Cascade system
Cooling system without PCA
Compressed air system

Door

Full size door
Automatic locking
Slot front door (constant loading level)
Full size sub-door
Cooling by cold water circuit

Process sensors

Pirani
Capacitive
Temperature probes (Pt-100 / Thermocouple)
Redundant temperature probes (Pt-100 / Thermocouple)
Wireless temperature monitoring
Full batch traceability software

Control systems

Rockwell / Siemens Automation PLC
Integrated HMI
SCADA
Electronic recorder
Electronic Server and Think Client
Cycle optimization technology

Filter vent system

Sterilizable
Ports for integrity testing
Secondary venting cycle
Secondary vent filter
Water filter integrity test

Vacuum system

Sealed vacuum pumps with blowing system
Redundancy (additional pump)
Dry pumps with blowing system

VLS + LyoPharm

Freeze dryer automatic loading and unloading system for vials

Freeze dryer automatic loading and unloading system for vials. Output up to 24,000 uph / From 2 to 45 m² of shelf area